Exam Master Neuro Practice Exam

In cases of suspected status epilepticus, the immediate goal is to terminate the seizure activity and stabilize the patient. Lorazepam is the preferred initial treatment due to its rapid onset of action and effectiveness in controlling seizures. It acts quickly to enhance the inhibitory neurotransmitter GABA at the synapse, which helps to stop the seizure activity and assist in regaining consciousness.

Lorazepam's pharmacokinetics allow it to act swiftly, often achieving therapeutic levels within minutes after administration when given intravenously. This fast-acting sedative effect is critical in an emergency, where delaying treatment may result in neurological damage.

While Phenytoin and Phenobarbital are used in the management of seizures, they are generally considered for secondary treatment after initial control has been established with a benzodiazepine like Lorazepam. IV glucose may be necessary if hypoglycemia is suspected, but it does not directly address the seizure activity in status epilepticus, making Lorazepam the most appropriate first-line option in this situation.